ElderCraft

ElderCraft Brochure (PDF)

Black Elderberry is widely known as a potent source ofantioxidants and for its immune supporting properties. ElderCraft® is a line of high-quality elderberry extractproducts manufactured using Austrian black elderberries (Sambucus nigra, L.) of the variety “Haschberg. ”ElderCraft® delivers standardized amounts of anthocyaninsin liquid or powdered formats. ElderCraft® is “crafted”using the IPT process, Iprona Polyphenol Technology, achemical-free process which enriches active compoundsincluding polyphenols and High Molecular WeightFractions.

Phytonutrient Profile

  • Contains nearly four times the anthocyanins as other commonly consumed berries
  • Unique anthocyanin profile containing cyanidin-3-glucoside, cyanidin-3,5-diglucoside, cyanidin-3-sambubioside, cyanidin- 3-sambubioside-5-glucoside
  • Rich in flavonoids like isoquercetin and catechins

Elderberry Benefits

  • Supports a healthy immune system
  • Promotes enhanced athletic performance
  • Promotes a healthy cardiovascular system
  • Promotes healthy aging and inflammation responses

Product Applications

Artemis’ elderberry liquids and powders are ideal for a variety of applications including functional foods and beverages, dietary supplements, and as natural colorants. They are suitable for use in capsules, tablets, drink mixes, cosmetics, and more.

Elderberry Berryceuticals®

Elderberry Juice Concentrate (65° Brix: organic)
Pure Elderberry (Sambucus nigra) juice concentrate.

Elderberry Juice Powder 5:1 (spray-dried concentrate, non-standardized, conventional & organic)
Pink-purple powder perfect for enhancing products naturally.

ElderCraft® 3.2% Liquid* (conventional & organic)
European black elderberry liquid standardized to a minimum anthocyanin content of 3.2%.

ElderCraft® 7% Powder* (conventional & organic)
Spray-dried European black elderberry extract standardized to a minimum anthocyanin content of 7%.

ElderCraft® 14% Powder* (conventional & organic)
Spray-dried European black elderberry extract standardized to a minimum anthocyanin content of 14%.

* IPT – Iprona Polyphenol Technology, a chemical-free process which enriches active compounds including polyphenols and High Molecular Weight Fractions.

Health Benefits

Elderberry has been extensively studied for bioavailability. In one particular human study by Cao et al. (2001), elderly women consumed an acute dosage of Artemis’ standardized elderberry extract, and anthocyanins were detected as glycosides in both plasma and urine. Further analysis of the urine by HPLC-MS/MS confirmed the existence of two main anthocyanins in elderberry (cyanidin-3-glucoside and cyanidin-3-sambubioside) as well as four metabolites. Other studies by Milbury and his team (2002) confirmed the absorption of anthocyanins in their glycosylated forms and identified various metabolized forms. Wu et al. (2002) discussed the fact that absorption from an extract will likely be better than from the raw plant where the anthocyanins have not been extracted from the plant cell.
Elderberry’s historical role in the treatment of colds and flu has stimulated much research interest. In a clinical trial conducted by Israeli scientists (Zakay-Rones et al., 1995), elderberry was administered to influenza-infected patients. Elderberry treatment resulted in reduced severity and longevity of flu symptoms. Also, research out of Germany (Krawitz et al., 2011) reported that Artemis’ elderberry extract inhibits the growth of influenza A and B viruses and bacteria associated with upper respiratory tract infections in humans. Artemis’ standardized elderberry extracts have been shown, in vitro, to possess additional antiviral activity, most notably against replication of HSV-1, HSV-2, and HCMV viruses. De Benito et al. (1998) isolated ribosome-inactivating proteins (RIP) in elderberries as well. RIPs may serve as a potential immunotoxin and can be used both as an antiviral and an antitumor agent. In studies by Blumenthal et al. (pending publication) it was shown that Artemis’ elderberry extracts enhance the immune system through increased levels of T cells, B cells, and IFN and IL-2 cytokines, resulting in an increased resistance to viral infection that was even more pronounced in older animals. This work also suggested that elderberry’s effect on enhancing the immune response may involve activation of genes that produce IL-2 and IFN and can act directly on viruses to inhibit their ability to replicate.
Using a model for monitoring critical care patients, researchers in Austria showed elderberry extracts reduced stress by mediating changes in blood parameters. When an elderberry extract was administered to athletes and highly stressed emergency responders, the results showed a positive impact on the subjects’ stress responses and exercise regimens. In effect, elderberry reduced the production of stress hormones, delayed and reduced lactic acid production, and kept the body in a state of oxidative phosphorylation longer, enabling longer/harder workouts.
Reactive oxygen species (ROS) play a critical role in the impairment of nitric oxide-mediated vascular functions and overall pathogenesis associated with cardiovascular disease. Abuja et al. (1998) showed that Artemis’ elderberry extract reduced the oxidation rates of low-density lipoprotein (LDL is known as the “bad cholesterol” as it generates free radicals when oxidation occurs). Additional studies have shown the effects of elderberry anthocyanins on vascular endothelium, which plays a crucial role in blood flow regulation and vascular tone. Studies by Youdim et al. (2000) revealed that enrichment of endothelial cells with Artemis’ elderberry anthocyanins conferred significant protective effects against diverse oxidative stressors—which can have important implications on preserving endothelial cell functions and preventing against vascular diseases. Bell et al. (2005) found that elderberry anthocyanins produced endothelium-dependent relaxation in porcine coronary arteries. Extract concentrations too low to directly alter coronary vascular tone protected coronary arteries from ROS without altering vasorelaxation to endogenous or exogenous nitric oxide. Tsuda et al. (1999) have also reported that elderberry anthocyanins suppressed oxidative stress in mouse models of liver ischemia. Researchers in Austria conducted a pilot study to look specifically at the potential effects of elderberry extract on fasting and postprandial risk profiles. They (Murkovic et al., 2000) found that anthocyanins from elderberry showed a total cholesterol lowering effect. Elderberry’s role in diabetes was also investigated by Gray et al. (2000) and subsequently by Ciocoiu et al. (2009). They reported that the anthocyanins stimulated insulin production and exhibited hypoglycemiant, hypolipemiant and antioxidant effects.

All elderberry products are also available in NOP certified organic upon request.